Depersonalization- Derealization Disorder and IS-TDP

Epidemiology of DDD

• Onset ≈ age of 16 ± 6 (95% before the age of 25)
• Men : women = 1:1
• Prevalence in the general population ≈ 1% (Yang et al. 2023)
• Outpatients 5-20% (Yang et al. 2023)
• Inpatients 17.5-41.9% (Yang et al. 2023)
• Administrative 12-month prevalence of DDD = 0.007% (Michal et al. 2010)
• Course mostly chronic and treatment-resistant, rarely episodic
• 15 or more years of permanent DP/DR are common
• ≈ 7 years until "diagnosis" (Sierra 2009)
• High comorbidity (depression, anxiety disorders, obsessive thoughts, substance
• abuse, personality disorders)